I've noticed some things running slower too, but I wasn't sure if my computer was getting older. As for the interface/asthetic, it's pretty terrible in every regard.
Readit NewsNeuroCoder commented on Tell HN: macOS 26 is making me have regrets for the first time in 12yrs · Posted by u/trumbitta2
A) incredible article, one of the few where I didn’t feel compelled to give up and find the underlying paper. Well written, beautiful diagrams, appreciably concise. Thanks for posting!
B) The image of ~starlings hanging out with dinosaurs blew my mind. Talk about an odd juxtaposition! But I’m no dinosaur nerd, and haven’t seen the new generation of shows.
C) I just have to nitpick this to defend my buddies:
Modern birds have some of the most advanced cognitive capabilities in the animal kingdom, comparable only with mammals.
The figures in the nature article are worth it. Even my non-nerdy wife thought it was kind of interesting.
NeuroCoder commented on Statistical Rethinking (2024 Edition) github.com/rmcelreath/sta... · Posted by u/lnyan
WHY do you think it’s bad for that background? Please!
What if you know math but not stats? How much stats do I need to know before you think this isn’t good to browse?
Wish I knew… I guess I’ll have to find out the hard way.
It's just very conversational. If you are comfortable with stats and just need a reference it can be obnoxious. I think I went through the first edition in my PhD and it was better than a stats course. But when I want a quick reference for something it is to much reading to get to the point. It might be more well organized now though.
NeuroCoder commented on Statistical Rethinking (2024 Edition) github.com/rmcelreath/sta... · Posted by u/lnyan
Honestly, I think there are very little prerequisites. I'm an MD dabbling into stats and found the book very well made as well as understandable.
As an MD/PhD I wish all MD researchers read this book. Heck, I wish all neuro researchers read it. If you are already established in in stats and math and your interest is just another math book to casually read or reference, this is a bad choice
NeuroCoder commented on A Case Against the Placebo Effect carcinisation.com/2024/11... · Posted by u/Luc
That were already proven to be stronger than placebo?
Usually we test against best current treatment and not just always against placebo. If something clearly improves outcomes for a patient, it's unethical to not give them a treatment so that you can test your new intervention against a placebo.
NeuroCoder commented on A Case Against the Placebo Effect carcinisation.com/2024/11... · Posted by u/Luc
Isn't stress known to reduce body's healing processes. Stress, lack of sleep and proper rest. If you believe something is taking care of you, you will have reduced stress, sleep and rest better. Wouldn't it be logical to expect faster healing. Also human bodies can heal naturally as well.
Stress increases cortisol and cortisol for a long time wrecks the immune system. There are a lot of other things that effect cortisol levels, but it's at least on very plausible pathway for some getting sick more easily.
I would hope so. The government paying private companies to spread its propaganda is bad for many reasons.
It's already an uphill battle to fix misinformation concerning vaccines without calling it political.
Article says this has been done other places already. Has this specifically been campaign ads or does it also involve things that are considered politically motivated messaging? For example, is there danger of vaccination PSAs getting banned because some politicians say bizarre things about them?
> These include Absence Seizures, when a person stops what they are doing altogether, loses awareness but does not collapse or have visible convulsions; Myoclonic Seizures, when a person’s limbs suddenly jerk uncontrollably but they remain conscious and aware; and Tonic Clonic Seizures where a person loses consciousness, collapses, and their whole body convulses.
I've witnessed something that I've never seen described anywhere – a very similar thing to an 'absence seizure', but the person is still aware and responding but seem unable to break away from the empty stare even when they try.
There are all kinds of presentations for seizures. Ones in the frontal lobe are particularly hard to catch based on external presentation. If one is suspected of having seizures they will get a continuously monitored EEG where times associated where the seizure like state is monitored electrically. Sometimes it's a really weird presentation of a seizure or sometimes it's psychogenic. Either way it's good to have these people get some help I'd it keeps happening.
It's taken 12 years to get from "this stuff exists in mice" to "we now know it actually exists in humans and is not vestigial". That seems like a long time. People get brain MRIs with contrast all the time, is there any reason why this never showed up? Because no one was looking? Or because it's a slow mechanism?
Two things:
1. Blood brain barrier and CSF should be separate for all but tiny molecules. It's why CT angiograms are able to visualize distinct vessels. So it is pretty hard to directly interact with this sort of thing in vivo
2. A good chunk of the neuro community have been operating under the assumption that some of those mouse model findings are mechanisms in humans too. Since we couldn't easily prove it, people used a bunch of next best tools with fancy imaging that demonstrated it was very likely. On top of furter proof, this sort of study allows us to begin pinpointing exactly how close our next best tools are at estimating in vivo processes without opening up the head.