IBD (including ulcerative colitis, which increases the risk of colorectal cancer dramatically) is also increasing in developed/westernized countries.[1]
It's unclear how much of this is is due to changes in diet, hygiene hypothesis, or environmental pollutants/endocrine disruptors.
My family has personally experienced this and it is terrifying to learn how little information and how few resources there are for young children with IBD.
Right out of the gate you hit the issue that there simply aren't many "very early onset IBD" (impacting children under 6 years old) specialists because historically there were so few cases. We've seen well regarded IBD specialists who reflexively try to order tests and procedures that their own hospital will then refuse to even perform because they can't be done safely on young children. The IBD specialists are in general simply unfamiliar with young children because of the historical rarity.
From the VEO IBD specialists we have worked with they all report that the numbers are exploding and no one has any real idea why.
On top of that most of the more modern and effective treatments for IBD and Crohns aren't approved for young children at all and even top tier insurance will fight tooth and nail against covering them because their use in children can be considered off-label.
Chloramine (chlorine and ammonia) in the water we drink has been linked to IBD, IBS and Crohn’s. Most large cities switched to this now in the US (San Francisco switched in 2004). It is also difficult to filter out of water. We shower in it too, vaporized into our lungs with hot water.
I'm 99% certain it's a new lack of fiber as the American diet becomes more attuned to meat and starch.
I would bet MONEY that if you looked at IBD rates among people who tend to frequent taco bell (lots of beans == lots of fiber) and people who tend to frequent, say, McD's, you'd see a lower rate among TB-goers. Doesn't seem like a hard experiment to set up.
Fiber supplementation can worsen symptoms of IBS as it draws water into the colon. "Just eat more fibre" is a knee jerk response of people unfamiliar with the science. These conditions are corelated to inflamation and often it's FODMAPs which are a major contributor.
Dennis Burkitt documented this in 1973[0][1]. Unfortunately "Don't Forget Fibre in your Diet" (1979) and "F-Plan Diet" (1983) have faded into history a bit.
Detergents, preservatives, pesticides and low quality ingredients are all great examples of things you can cut out eating at home. While we don't seem to have enough data to point to each one of them individually, it seems pretty common sense these are the new contributing factors in our environment.
Lectins, specifically gluten, are strongly associated with IBS. Many people have found relief from IBS by reducing or eliminating lectins in their diet, especially gluten. It is worth pointing out that wheat is an extremely common ingredient nowadays, but most of the wheat we grow and eat is no longer the traditional emmer or einkorn but a dwarf hybrid that among other differences produces extreme amounts of gluten.
GF support groups are full of tales from people who were able to eat wheat in Europe but not NA.
What they don't tell you about wheat very often is that people figured out that if you defoliate a wheat plant, it will shove its remaining calories into the developing seeds and then die. You can control the maturity of a wheat field by spraying it with RoundUp late in the season.
So where the reality versus PR for the decay rate of RoundUp in the environment leaves a very long safety margin with early season and pre-emergent uses of the stuff, whatever you sprayed a matter of weeks before harvest very much matters on variance between fields and between customer and manufacturer.
What you say is true, but the hybrid wheat rich in gluten has already existed for a few millennia and during all this time it has been the main staple food for hundreds of millions or even for billions of people, who have suffered no undesirable consequences from it.
Nowadays it seems that there are more and more people that are affected negatively by gluten consumption. Because this was much less frequent in the past, there must be an additional unidentified factor that causes gluten sensitivity and which has not existed formerly.
Isn’t that article contradicting your point? They weren’t able to find any effect for dish detergent, and the effect they did find for rinse aids was not present at the concentrations used in residential dishwashers?
I just checked, and my detergent (Finish Quantum) has alcohol ethoxylates in it. I wonder if with newer high efficiency dishwashers that use less water, this stuff isn't getting rinsed off as well.
> "Interestingly, detergent residue from professional dishwashers demonstrated the remnant of a significant amount of cytotoxic and epithelial barrier–damaging rinse aid remaining on washed and ready-to-use dishware."
Because the linked research does not support the point the poster is making. The researchers did not find a link with dishwasher detergents. They found a link with rinse aids, but at quantities and concentrations far higher than you'd find in a dishwasher.
Also, I think we should all be skeptical of someone who says, essentially, "Don't want colorectal cancer? Rinse your dishes and don't eat at restaurants!" Such a simple explanation for colorectal cancer seems suspicious... at best.
This rapid increase is especially puzzling because the rate of colorectal cancer has plummeted among older adults—largely due to regular colonoscopies and lower rates of smoking.
“We don’t understand a lot about the causes, the biology, or how to prevent early onset of the disease,” said Phil Daschner, a program director in NCI’s Division of Cancer Biology. “And that’s important to learn more about because it may affect [approaches for] the treatment and survivorship of early-onset colon cancer.”
The cited paper is not sufficient to explain the dramatic rise. It would have been seen much earlier (since the 50s) that the trend was obvious. Putting forth "just do X" is a low effort post. It has a paper, which is something, but it's far from definitive, although it's phrased as such.
I'm sure someone thought the same as me, but they thought clicking the down button was the correct response. I don't agree, but I understand that not everyone is put together before the coffee kicks in.
I have had 2 quarter-coin sized growths removed from my colon. The underlying cause is undiagnosed. They were not cancerous, by analysis. I believe the growths started in Washington State 6ish years ago and black mold was a contributor, with other factors. Growths have not returned.
I'd start with gastroenterologists. I've started having some GI issues recently so I've been seeing one, but there was a 4+ week wait time to see anyone in my area.
Seconding a gastroenterologist. In Australia you have to be referred to by a general physician, and the GE will perform the colonoscopy procedure and also consult. I'm in my 30s and had mine done just the other week. The prep sucks but it's for a good cause, and the anaesthesia is divine.
Good on your friend ;) It's important to look after your brain's meat suit, particularly that area considering the growing body of research between the gut/brain
Could it be from people sitting on their butt all day? Not like, not working, but just physically constantly sitting? I don't think our ancestors spent most of their waking hours sitting down.
Fake foods, low vitamin D, iron shavings supplementation in flour -> bad vitamin B status, bad intestinal bacteria, intestinal damage -> chronic inflammation -> cancer
I'm guessing fake foods overloaded with preservatives... much like with increased oxidative stress in general.
edit:
noting: "There’s mounting evidence linking an unhealthy diet—in particular, one high in processed meat and fat, and low in fruits and vegetables—to early-onset colorectal cancer."
Sounds like it's the meat/fat/cholesterol myth 2.0 ... Not that I'm massively in favor of overly processed meat... but the body needs fat... we're still suffering from the hormone production issues a half century of disinformation on dietary fat has lead to... and the heart disease over a century of processed fats in unnatural ratios has lead to.
Fruits and Vegetables are not naturally available year-round, anywhere. If you want to choose to be vegetarian, cool... but to assume it's meat (part what makes us human for many millenia) and not the processed "foods" that didn't even exist 150 years ago is just absurd.
A quick google search says gay men have cancer rates double or more than straight men, so maybe. The article doesn't mention it so they either don't think it could be linked or wanted to avoid that subject since it would obviously be a touchy one. Although, if they do think there is a connection, it does seem like it would be important to target education to those who have anal sex so they know to get more screenings.
Readit News
It's unclear how much of this is is due to changes in diet, hygiene hypothesis, or environmental pollutants/endocrine disruptors.
I wish we understood this better.
[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020403/
Right out of the gate you hit the issue that there simply aren't many "very early onset IBD" (impacting children under 6 years old) specialists because historically there were so few cases. We've seen well regarded IBD specialists who reflexively try to order tests and procedures that their own hospital will then refuse to even perform because they can't be done safely on young children. The IBD specialists are in general simply unfamiliar with young children because of the historical rarity.
From the VEO IBD specialists we have worked with they all report that the numbers are exploding and no one has any real idea why.
On top of that most of the more modern and effective treatments for IBD and Crohns aren't approved for young children at all and even top tier insurance will fight tooth and nail against covering them because their use in children can be considered off-label.
I would bet MONEY that if you looked at IBD rates among people who tend to frequent taco bell (lots of beans == lots of fiber) and people who tend to frequent, say, McD's, you'd see a lower rate among TB-goers. Doesn't seem like a hard experiment to set up.
Are we sure Taco Bell has not discovered a novel way to remove important nutrients from this item as well?
[0]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1588096/ [1]: https://en.wikipedia.org/wiki/Denis_Parsons_Burkitt
Deleted Comment
- you
https://www.jacionline.org/article/S0091-6749(22)01477-4/ful...
Detergents, preservatives, pesticides and low quality ingredients are all great examples of things you can cut out eating at home. While we don't seem to have enough data to point to each one of them individually, it seems pretty common sense these are the new contributing factors in our environment.
What they don't tell you about wheat very often is that people figured out that if you defoliate a wheat plant, it will shove its remaining calories into the developing seeds and then die. You can control the maturity of a wheat field by spraying it with RoundUp late in the season.
So where the reality versus PR for the decay rate of RoundUp in the environment leaves a very long safety margin with early season and pre-emergent uses of the stuff, whatever you sprayed a matter of weeks before harvest very much matters on variance between fields and between customer and manufacturer.
We may be feeding ourselves RoundUp here.
Nowadays it seems that there are more and more people that are affected negatively by gluten consumption. Because this was much less frequent in the past, there must be an additional unidentified factor that causes gluten sensitivity and which has not existed formerly.
Emmer contains twice as much gluten as modern wheat according to this summary paper of chemical composition, see table 3: https://www.researchgate.net/profile/Anna-Zaparenko/publicat...
Deleted Comment
From their results section:
> "Interestingly, detergent residue from professional dishwashers demonstrated the remnant of a significant amount of cytotoxic and epithelial barrier–damaging rinse aid remaining on washed and ready-to-use dishware."
Also, I think we should all be skeptical of someone who says, essentially, "Don't want colorectal cancer? Rinse your dishes and don't eat at restaurants!" Such a simple explanation for colorectal cancer seems suspicious... at best.
This rapid increase is especially puzzling because the rate of colorectal cancer has plummeted among older adults—largely due to regular colonoscopies and lower rates of smoking.
“We don’t understand a lot about the causes, the biology, or how to prevent early onset of the disease,” said Phil Daschner, a program director in NCI’s Division of Cancer Biology. “And that’s important to learn more about because it may affect [approaches for] the treatment and survivorship of early-onset colon cancer.”
Deleted Comment
Dead Comment
Dead Comment
Though I would de-prioritize "rinse your dishes" and say the food we eat is more of the issue.
Is there some logical reason you would down vote without any explanation or counter argument?
I'm sure someone thought the same as me, but they thought clicking the down button was the correct response. I don't agree, but I understand that not everyone is put together before the coffee kicks in.
I have had 2 quarter-coin sized growths removed from my colon. The underlying cause is undiagnosed. They were not cancerous, by analysis. I believe the growths started in Washington State 6ish years ago and black mold was a contributor, with other factors. Growths have not returned.
Good on your friend ;) It's important to look after your brain's meat suit, particularly that area considering the growing body of research between the gut/brain
Dead Comment
edit:
noting: "There’s mounting evidence linking an unhealthy diet—in particular, one high in processed meat and fat, and low in fruits and vegetables—to early-onset colorectal cancer."
Sounds like it's the meat/fat/cholesterol myth 2.0 ... Not that I'm massively in favor of overly processed meat... but the body needs fat... we're still suffering from the hormone production issues a half century of disinformation on dietary fat has lead to... and the heart disease over a century of processed fats in unnatural ratios has lead to.
Fruits and Vegetables are not naturally available year-round, anywhere. If you want to choose to be vegetarian, cool... but to assume it's meat (part what makes us human for many millenia) and not the processed "foods" that didn't even exist 150 years ago is just absurd.
[0] https://www.mayoclinic.org/prebiotics-probiotics-and-your-he...
Dead Comment
If you are bottoming a lot you can consider screening for that every 1-3 years.
Deleted Comment